The smart Trick of login thr777 That No One is Discussing

Comment: This sequence alter influences codon 777 on the GAA mRNA. It is just a 'silent' adjust, meaning that it does not alter the encoded amino acid sequence from the GAA protein. This variant also falls at the last nucleotide of exon sixteen, which is Element of the consensus splice web-site for this exon. This variant is current in inhabitants databases (rs375311693, gnomAD 0.03%). This variant hasn't been claimed inside the literature in individuals afflicted with GAA-similar circumstances.

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Stars symbolize the mixture overview position, or the extent of evaluation supporting the mixture germline classification for this VCV report.

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This date signifies the final time this VCV report was up-to-date. The update can be as a consequence of an update to on the list of bundled submitted documents (SCVs), or resulting from an update that ClinVar built to your variant for instance link alternatif thr777 incorporating HGVS expressions or even a rs quantity.

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